Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade.
Nat Genet   (2012 Aug 5)
Tachibana SI, Sullivan SA, Kawai S, Nakamura S, Kim HR, Goto N, Arisue N, Palacpac NM, Honma H, Yagi M, Tougan T, Katakai Y, Kaneko O, Mita T, Kita K, Yasutomi Y, Sutton PL, Shakhbatyan R, Horii T, Yasunaga T, Barnwell JW, Escalante AA, Carlton JM, Tanabe K
The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum.
Nat Genet   (2012 Aug 5)
Neafsey DE, Galinsky K, Jiang RH, Young L, Sykes SM, Saif S, Gujja S, Goldberg JM, Young S, Zeng Q, Chapman SB, Dash AP, Anvikar AR, Sutton PL, Birren BW, Escalante AA, Barnwell JW, Carlton JM
Extensive genetic diversity, unique population structure and evidence of genetic exchange in the sexually transmitted parasite Trichomonas vaginalis.
PLoS Negl Trop Dis   (2012)
Conrad MD, Gorman AW, Schillinger JA, Fiori PL, Arroyo R, Malla N, Dubey ML, Gonzalez J, Blank S, Secor WE, Carlton JM
The complexities of malaria disease manifestations with a focus on asymptomatic malaria.
Malar J   (2012)
Laishram DD, Sutton PL, Nanda N, Sharma VL, Sobti RC, Carlton JM, Joshi H
Malaria in India: the center for the study of complex malaria in India.
Acta Trop   (2012 Mar)
Das A, Anvikar AR, Cator LJ, Dhiman RC, Eapen A, Mishra N, Nagpal BN, Nanda N, Raghavendra K, Read AF, Sharma SK, Singh OP, Singh V, Sinnis P, Srivastava HC, Sullivan SA, Sutton PL, Thomas MB, Carlton JM, Valecha N
The evolution of infectious agents in relation to sex in animals and humans: brief discussions of some individual organisms.
Ann N Y Acad Sci   (2011 Aug)
Reed DL, Currier RW, Walton SF, Conrad M, Sullivan SA, Carlton JM, Read TD, Severini A, Tyler S, Eberle R, Johnson WE, Silvestri G, Clarke IN, Lagergard T, Lukehart SA, Unemo M, Shafer WM, Beasley RP, Bergstrom T, Norberg P, Davison AJ, Sharp PM, Hahn BH, Blomberg J
Why is Plasmodium vivax a neglected tropical disease?
PLoS Negl Trop Dis   (2011 Jun)
Carlton JM, Sina BJ, Adams JH
Phylogeny of parasitic parabasalia and free-living relatives inferred from conventional markers vs. Rpb1, a single-copy gene.
PLoS One   (2011)
Malik SB, Brochu CD, Bilic I, Yuan J, Hess M, Logsdon JM Jr, Carlton JM
Linkage maps from multiple genetic crosses and loci linked to growth-related virulent phenotype in Plasmodium yoelii.
Proc Natl Acad Sci U S A   (2011 Aug 2)
Li J, Pattaradilokrat S, Zhu F, Jiang H, Liu S, Hong L, Fu Y, Koo L, Xu W, Pan W, Carlton JM, Kaneko O, Carter R, Wootton JC, Su XZ
Genome sequences reveal divergence times of malaria parasite lineages.
Parasitology   (2011 Nov)
Silva JC, Egan A, Friedman R, Munro JB, Carlton JM, Hughes AL
Microsatellite polymorphism in the sexually transmitted human pathogen Trichomonas vaginalis indicates a genetically diverse parasite.
Mol Biochem Parasitol   (2011 Jan)
Conrad M, Zubacova Z, Dunn LA, Upcroft J, Sullivan SA, Tachezy J, Carlton JM
Predicting malaria interactome classifications from time-course transcriptomic data along the intraerythrocytic developmental cycle.
Artif Intell Med   (2010 Jul)
Mitrofanova A, Kleinberg S, Carlton J, Kasif S, Mishra B
A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito.
PLoS Negl Trop Dis   (2010)
Westenberger SJ, McClean CM, Chattopadhyay R, Dharia NV, Carlton JM, Barnwell JW, Collins WE, Hoffman SL, Zhou Y, Vinetz JM, Winzeler EA
Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite.
Lancet Infect Dis   (2009 Sep)
Mueller I, Galinski MR, Baird JK, Carlton JM, Kochar DK, Alonso PL, del Portillo HA
Hundreds of microsatellites for genotyping Plasmodium yoelii parasites.
Mol Biochem Parasitol   (2009 Aug)
Li J, Zhang Y, Liu S, Hong L, Sullivan M, McCutchan TF, Carlton JM, Su XZ
Carotenoid biosynthesis in intraerythrocytic stages of Plasmodium falciparum.
J Biol Chem   (2009 Apr 10)
Tonhosolo R, D'Alexandri FL, de Rosso VV, Gazarini ML, Matsumura MY, Peres VJ, Merino EF, Carlton JM, Wunderlich G, Mercadante AZ, Kimura EA, Katzin AM
IDEA: Interactive Display for Evolutionary Analyses.
BMC Bioinformatics   (2008)
Egan A, Mahurkar A, Crabtree J, Badger JH, Carlton JM, Silva JC
Comparative evolutionary genomics of human malaria parasites.
Trends Parasitol   (2008 Dec)
Carlton JM, Escalante AA, Neafsey D, Volkman SK
The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites.
Proc Natl Acad Sci U S A   (2008 Oct 21)
Bozdech Z, Mok S, Hu G, Imwong M, Jaidee A, Russell B, Ginsburg H, Nosten F, Day NP, White NJ, Carlton JM, Preiser PR
Comparative genomics of the neglected human malaria parasite Plasmodium vivax.
Nature   (2008 Oct 9)
Carlton JM, Adams JH, Silva JC, Bidwell SL, Lorenzi H, Caler E, Crabtree J, Angiuoli SV, Merino EF, Amedeo P, Cheng Q, Coulson RM, Crabb BS, Del Portillo HA, Essien K, Feldblyum TV, Fernandez-Becerra C, Gilson PR, Gueye AH, Guo X, Kang'a S, Kooij TW, Korsinczky M, Meyer EV, Nene V, Paulsen I, White O, Ralph SA, Ren Q, Sargeant TJ, Salzberg SL, Stoeckert CJ, Sullivan SA, Yamamoto MM, Hoffman SL, Wortman JR, Gardner MJ, Galinski MR, Barnwell JW, Fraser-Liggett CM
GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalis.
Nucleic Acids Res   (2009 Jan)
Aurrecoechea C, Brestelli J, Brunk BP, Carlton JM, Dommer J, Fischer S, Gajria B, Gao X, Gingle A, Grant G, Harb OS, Heiges M, Innamorato F, Iodice J, Kissinger JC, Kraemer E, Li W, Miller JA, Morrison HG, Nayak V, Pennington C, Pinney DF, Roos DS, Ross C, Stoeckert CJ Jr, Sullivan S, Treatman C, Wang H
Plasmodium vivax in India.
Trends Parasitol   (2008 May)
Joshi H, Prajapati SK, Verma A, Kang'a S, Carlton JM
Local adaptation and vector-mediated population structure in Plasmodium vivax malaria.
Mol Biol Evol   (2008 Jun)
Joy DA, Gonzalez-Ceron L, Carlton JM, Gueye A, Fay M, McCutchan TF, Su XZ
Evidence-based annotation of the malaria parasite's genome using comparative expression profiling.
PLoS One   (2008)
Zhou Y, Ramachandran V, Kumar KA, Westenberger S, Refour P, Zhou B, Li F, Young JA, Chen K, Plouffe D, Henson K, Nussenzweig V, Carlton J, Vinetz JM, Duraisingh MT, Winzeler EA
Contrasting genetic structure in Plasmodium vivax populations from Asia and South America.
Int J Parasitol   (2007 Jul)
Imwong M, Nair S, Pukrittayakamee S, Sudimack D, Williams JT, Mayxay M, Newton PN, Kim JR, Nandy A, Osorio L, Carlton JM, White NJ, Day NP, Anderson TJ
Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites.
J Infect Dis   (2007 Apr 1)
Imwong M, Snounou G, Pukrittayakamee S, Tanomsing N, Kim JR, Nandy A, Guthmann JP, Nosten F, Carlton J, Looareesuwan S, Nair S, Sudimack D, Day NP, Anderson TJ, White NJ
Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis.
Science   (2007 Jan 12)
Carlton JM, Hirt RP, Silva JC, Delcher AL, Schatz M, Zhao Q, Wortman JR, Bidwell SL, Alsmark UC, Besteiro S, Sicheritz-Ponten T, Noel CJ, Dacks JB, Foster PG, Simillion C, Van de Peer Y, Miranda-Saavedra D, Barton GJ, Westrop GD, Muller S, Dessi D, Fiori PL, Ren Q, Paulsen I, Zhang H, Bastida-Corcuera FD, Simoes-Barbosa A, Brown MT, Hayes RD, Mukherjee M, Okumura CY, Schneider R, Smith AJ, Vanacova S, Villalvazo M, Haas BJ, Pertea M, Feldblyum TV, Utterback TR, Shu CL, Osoegawa K, de Jong PJ, Hrdy I, Horvathova L, Zubacova Z, Dolezal P, Malik SB, Logsdon JM Jr, Henze K, Gupta A, Wang CC, Dunne RL, Upcroft JA, Upcroft P, White O, Salzberg SL, Tang P, Chiu CH, Lee YS, Embley TM, Coombs GH, Mottram JC, Tachezy J, Fraser-Liggett CM, Johnson PJ
Toward a malaria haplotype map.
Nat Genet   (2007 Jan)
Carlton JM
Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote.
PLoS Biol   (2006 Sep)
Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK Jr, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA, Krieger CJ, del Toro C, Ryder HF, Williamson SC, Barbeau RA, Hamilton EP, Orias E
Lineage-specific expansion of proteins exported to erythrocytes in malaria parasites.
Genome Biol   (2006)
Sargeant TJ, Marti M, Caler E, Carlton JM, Simpson K, Speed TP, Cowman AF
A Plasmodium whole-genome synteny map: indels and synteny breakpoints as foci for species-specific genes.
PLoS Pathog   (2005 Dec)
Kooij TW, Carlton JM, Bidwell SL, Hall N, Ramesar J, Janse CJ, Waters AP
Comparative genomics of malaria parasites.
Curr Opin Genet Dev   (2005 Dec)
Hall N, Carlton J
Identification of a very large Rab GTPase family in the parasitic protozoan Trichomonas vaginalis.
Mol Biochem Parasitol   (2005 Oct)
Lal K, Field MC, Carlton JM, Warwicker J, Hirt RP
Gene discovery in Plasmodium vivax through sequencing of ESTs from mixed blood stages.
Mol Biochem Parasitol   (2005 Nov)
Cui L, Fan Q, Hu Y, Karamycheva SA, Quackenbush J, Khuntirat B, Sattabongkot J, Carlton JM
Comparative genomics of trypanosomatid parasitic protozoa.
Science   (2005 Jul 15)
El-Sayed NM, Myler PJ, Blandin G, Berriman M, Crabtree J, Aggarwal G, Caler E, Renauld H, Worthey EA, Hertz-Fowler C, Ghedin E, Peacock C, Bartholomeu DC, Haas BJ, Tran AN, Wortman JR, Alsmark UC, Angiuoli S, Anupama A, Badger J, Bringaud F, Cadag E, Carlton JM, Cerqueira GC, Creasy T, Delcher AL, Djikeng A, Embley TM, Hauser C, Ivens AC, Kummerfeld SK, Pereira-Leal JB, Nilsson D, Peterson J, Salzberg SL, Shallom J, Silva JC, Sundaram J, Westenberger S, White O, Melville SE, Donelson JE, Andersson B, Stuart KD, Hall N
Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes.
Science   (2005 Jul 1)
Gardner MJ, Bishop R, Shah T, de Villiers EP, Carlton JM, Hall N, Ren Q, Paulsen IT, Pain A, Berriman M, Wilson RJ, Sato S, Ralph SA, Mann DJ, Xiong Z, Shallom SJ, Weidman J, Jiang L, Lynn J, Weaver B, Shoaibi A, Domingo AR, Wasawo D, Crabtree J, Wortman JR, Haas B, Angiuoli SV, Creasy TH, Lu C, Suh B, Silva JC, Utterback TR, Feldblyum TV, Pertea M, Allen J, Nierman WC, Taracha EL, Salzberg SL, White OR, Fitzhugh HA, Morzaria S, Venter JC, Fraser CM, Nene V
Immune responses to Plasmodium vivax pre-erythrocytic stage antigens in naturally exposed Duffy-negative humans: a potential model for identification of liver-stage antigens.
Eur J Immunol   (2005 Jun)
Wang R, Arevalo-Herrera M, Gardner MJ, Bonelo A, Carlton JM, Gomez A, Vera O, Soto L, Vergara J, Bidwell SL, Domingo A, Fraser CM, Herrera S
Host switch leads to emergence of Plasmodium vivax malaria in humans.
Mol Biol Evol   (2005 Aug)
Mu J, Joy DA, Duan J, Huang Y, Carlton J, Walker J, Barnwell J, Beerli P, Charleston MA, Pybus OG, Su XZ
Spliceosomal introns in the deep-branching eukaryote Trichomonas vaginalis.
Proc Natl Acad Sci U S A   (2005 Mar 22)
Vanacova S, Yan W, Carlton JM, Johnson PJ
A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses.
Science   (2005 Jan 7)
Hall N, Karras M, Raine JD, Carlton JM, Kooij TW, Berriman M, Florens L, Janssen CS, Pain A, Christophides GK, James K, Rutherford K, Harris B, Harris D, Churcher C, Quail MA, Ormond D, Doggett J, Trueman HE, Mendoza J, Bidwell SL, Rajandream MA, Carucci DJ, Yates JR 3rd, Kafatos FC, Janse CJ, Barrell B, Turner CM, Waters AP, Sinden RE
Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment.
Nature   (2004 Dec 16)
Moran MA, Buchan A, Gonzalez JM, Heidelberg JF, Whitman WB, Kiene RP, Henriksen JR, King GM, Belas R, Fuqua C, Brinkac L, Lewis M, Johri S, Weaver B, Pai G, Eisen JA, Rahe E, Sheldon WM, Ye W, Miller TR, Carlton J, Rasko DA, Paulsen IT, Ren Q, Daugherty SC, Deboy RT, Dodson RJ, Durkin AS, Madupu R, Nelson WC, Sullivan SA, Rosovitz MJ, Haft DH, Selengut J, Ward N
The genome of model malaria parasites, and comparative genomics.
Curr Issues Mol Biol   (2005 Jan)
Carlton J, Silva J, Hall N
Gene synteny and chloroquine resistance in Plasmodium chabaudi.
Mol Biochem Parasitol   (2004 Aug)
Hunt P, Martinelli A, Fawcett R, Carlton J, Carter R, Walliker D
A potentially functional mariner transposable element in the protist Trichomonas vaginalis.
Mol Biol Evol   (2005 Jan)
Silva JC, Bastida F, Bidwell SL, Johnson PJ, Carlton JM
Mind the gap: bridging the divide between clinical and molecular studies of the trichomonads.
Trends Parasitol   (2004 May)
Lyons EJ, Carlton JM
Novel antigen identification method for discovery of protective malaria antigens by rapid testing of DNA vaccines encoding exons from the parasite genome.
Infect Immun   (2004 Mar)
Haddad D, Bilcikova E, Witney AA, Carlton JM, White CE, Blair PL, Chattopadhyay R, Russell J, Abot E, Charoenvit Y, Aguiar JC, Carucci DJ, Weiss WR
Chloroquine resistance in Plasmodium chabaudi: are chloroquine-resistance transporter (crt) and multi-drug resistance (mdr1) orthologues involved?
Mol Biochem Parasitol   (2004 Jan)
Hunt P, Cravo PV, Donleavy P, Carlton JM, Walliker D
Genome sequencing and comparative genomics of tropical disease pathogens.
Cell Microbiol   (2003 Dec)
Carlton JM
Identification of a polymorphic Plasmodium vivax microsatellite marker.
Am J Trop Med Hyg   (2003 Oct)
Gomez JC, McNamara DT, Bockarie MJ, Baird JK, Carlton JM, Zimmerman PA
Plasmepsin 4, the food vacuole aspartic proteinase found in all Plasmodium spp. infecting man.
Mol Biochem Parasitol   (2003 Aug 11)
Dame JB, Yowell CA, Omara-Opyene L, Carlton JM, Cooper RA, Li T
Single-nucleotide polymorphisms and genome diversity in Plasmodium vivax.
Proc Natl Acad Sci U S A   (2003 Jul 8)
Feng X, Carlton JM, Joy DA, Mu J, Furuya T, Suh BB, Wang Y, Barnwell JW, Su XZ
The Plasmodium vivax genome sequencing project.
Trends Parasitol   (2003 May)
Carlton J
Genetics of mefloquine resistance in the rodent malaria parasite Plasmodium chabaudi.
Antimicrob Agents Chemother   (2003 Feb)
Cravo PV, Carlton JM, Hunt P, Bisoni L, Padua RA, Walliker D
Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14.
Nature   (2002 Oct 3)
Gardner MJ, Shallom SJ, Carlton JM, Salzberg SL, Nene V, Shoaibi A, Ciecko A, Lynn J, Rizzo M, Weaver B, Jarrahi B, Brenner M, Parvizi B, Tallon L, Moazzez A, Granger D, Fujii C, Hansen C, Pederson J, Feldblyum T, Peterson J, Suh B, Angiuoli S, Pertea M, Allen J, Selengut J, White O, Cummings LM, Smith HO, Adams MD, Venter JC, Carucci DJ, Hoffman SL, Fraser CM
Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii.
Nature   (2002 Oct 3)
Carlton JM, Angiuoli SV, Suh BB, Kooij TW, Pertea M, Silva JC, Ermolaeva MD, Allen JE, Selengut JD, Koo HL, Peterson JD, Pop M, Kosack DS, Shumway MF, Bidwell SL, Shallom SJ, van Aken SE, Riedmuller SB, Feldblyum TV, Cho JK, Quackenbush J, Sedegah M, Shoaibi A, Cummings LM, Florens L, Yates JR, Raine JD, Sinden RE, Harris MA, Cunningham DA, Preiser PR, Bergman LW, Vaidya AB, van Lin LH, Janse CJ, Waters AP, Smith HO, White OR, Salzberg SL, Venter JC, Fraser CM, Hoffman SL, Gardner MJ, Carucci DJ
Genome sequence of the human malaria parasite Plasmodium falciparum.
Nature   (2002 Oct 3)
Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B
Fast algorithms for large-scale genome alignment and comparison.
Nucleic Acids Res   (2002 Jun 1)
Delcher AL, Phillippy A, Carlton J, Salzberg SL
The shikimate pathway and its branches in apicomplexan parasites.
J Infect Dis   (2002 Feb 15)
Roberts CW, Roberts F, Lyons RE, Kirisits MJ, Mui EJ, Finnerty J, Johnson JJ, Ferguson DJ, Coggins JR, Krell T, Coombs GH, Milhous WK, Kyle DE, Tzipori S, Barnwell J, Dame JB, Carlton J, McLeod R
Rodent models of malaria in the genomics era.
Trends Parasitol   (2002 Mar)
Carlton JM, Carucci DJ